ZDCM-04

Introduction

ZDCM-04 is 1,3-dimethyl-7-{2-[1-(4-chloro-2,5-dimethoxyphenyl)propan-2-ylamino]ethyl}purine-2,6-dione. It links a 2,5-dimethoxy-4-chloroamphetamine (DOC) side chain to a theophylline ring through an ethylamino bridge, the same linker pattern used in fenethylline, which joins amphetamine to theophylline. The code DOC-fenethylline refers to that analogy.

It is a designer substance, reported from seized samples and controlled in Italy from March 2020. Published human pharmacology is lacking. Cleavage to DOC and a xanthine is a structural hypothesis, not a demonstrated metabolic pathway on a certificate. It is not an approved medicine. The label must state racemate versus enantiomer, because the propan-2-amine carbon is a stereocenter.

Key features and benefits – Buy ZDCM-04

• Defined conjugate. The 4-chloro-2,5-dimethoxyphenyl ring and the 1,3-dimethylxanthine distinguish it from DOC and from fenethylline.
• Documented formula. C20H26ClN5O4, molar mass 435.91 g·mol−1, PubChem CID 163192621.
• Chlorine marker. Mass spectra should show an M / M+2 pair.
• Reference solid. Suitable for identification work when the COA confirms the intact conjugate, not free DOC.
• Laboratory-only handling. Intended for controlled chemical and in vitro work, not for formulation or human administration.

Specifications of Buy ZDCM-04

Applications in research

Appropriate uses are non-clinical and institutionally approved:

• Analytical reference material for HPLC, LC-MS, and NMR identification of the intact conjugate.
• Forensic differentiation from DOC, fenethylline, and other dimethoxyamphetamine conjugates.
• Stability studies that look for cleavage under controlled chemical conditions.
• Impurity profiling, including residual DOC.

Do not describe or imply ingestion or any other human route. Do not treat the fenethylline analogy as a use instruction.

Purity and testing

A defensible product claim rests on the batch certificate.

• HPLC for chromatographic purity against a stated method, with a check that the main peak is the conjugate and not free DOC.
• 1H NMR for the 2,5-dimethoxy-4-chloro ring, the xanthine N-methyls, and the ethylamino bridge.
• Mass spectrometry for the molecular ion consistent with C20H26ClN5O4, including the chlorine isotope pair.
• Statement of racemate versus enantiomer.
• Residual solvent if the supplier states it.

Store the COA with the lot number. Do not label the product with a DOC CAS number.

Disclaimer

For laboratory research use only. Not for human or veterinary consumption, not for diagnostic or therapeutic use, and not a food, drug, or cosmetic. ZDCM-04 is illegal in Italy. DOC, the related phenethylamine, is a Schedule I controlled substance in the United States, and analogue rules may apply to this conjugate. Other jurisdictions may control it as a novel psychoactive substance. Buyers are responsible for confirming legality, licensing, import rules, and institutional approval before ordering or handling. Handle with standard laboratory PPE and dispose of waste under local hazardous-chemical rules. No statement on this page is a claim of safety, efficacy, or fitness for any human application.

Frequently asked questions

What is ZDCM-04?
It is a theophylline conjugate of the DOC side chain, formula C20H26ClN5O4. The listing name DOC-fenethylline describes that structure. It is not fenethylline and it is not DOC.

Does it have a CAS number?
No widely assigned CAS was found for the conjugate. Identity should be tied to the IUPAC name, formula, and PubChem CID 163192621, not to the CAS of DOC or theophylline.

Is this the same as DOC?
No. DOC is 2,5-dimethoxy-4-chloroamphetamine. ZDCM-04 adds a 1,3-dimethylxanthine through an ethylamino linker. They must be assayed separately.

What purity is supplied?
Only the figure on the lot COA. A page-level claim such as ≥98% by HPLC should match the method used for that batch and should show the intact conjugate.

How should it be stored?
Sealed, cool, dry, and protected from light. Record the lot number with the COA.

Can it be used in humans?
No. It is not an approved medicine and is not sold for consumption. It is illegal in Italy. Check local law before purchase.

What analytical methods confirm identity?
HPLC purity, NMR for the dimethoxy-chloro ring and the xanthine, and mass spectrometry consistent with C20H26ClN5O4, including the chlorine isotope pair. The COA should state racemate or enantiomer.