Phenibut HCl Powder

Introduction

Phenibut HCl powder is 4-amino-3-phenylbutanoic acid hydrochloride, also called fenibut or β-phenyl-GABA. A phenyl ring sits on the 3-position of GABA. The hydrochloride is the common weighable salt. The free acid is CAS 1078-21-3 and weighs 179.22 g·mol−1. The 1:1 hydrochloride weighs about 215.7 g·mol−1.

The beta carbon is a stereocenter. Clinical literature often refers to the (R) enantiomer. Many research lots are the racemate. The certificate must say which is supplied. Phenibut has been used as a medicine in some countries and sold as a supplement in others. It is not an FDA-approved drug in the United States. Authorities have warned about dependence and withdrawal with supplement use. This powder is supplied for analytical and in vitro research only.

Key features and benefits – Buy Phenibut HCl Powder

• Defined GABA analogue. The 3-phenyl group distinguishes it from GABA, baclofen (which is 4-chloro), and gabapentin.
• Hydrochloride form. The salt is a crystalline solid and is more water-soluble than the free acid. Formula weight must be the salt weight.
• Documented parent identity. Free acid CAS 1078-21-3, PubChem CID 14113, formula C10H13NO2.
• Stereochemistry stated. Racemate and (R)-phenibut are not interchangeable in an assay.
• Laboratory-only handling. Intended for controlled chemical and in vitro work, not as a dietary supplement.

Specifications Of Buy Phenibut HCl Powder

Applications in research

Appropriate uses are non-clinical and institutionally approved:

• Analytical reference for HPLC, LC-MS, and NMR identification of phenibut.
• Comparison of racemate and (R)-phenibut, and of free acid versus hydrochloride.
• GABA-B receptor assays where the protocol covers this compound.
• Forensic screening of powders labeled phenibut.
• Impurity profiling, including residual free acid or the wrong isomer.

Do not describe or imply oral use or any supplement protocol.

Purity and testing

A defensible product claim rests on the batch certificate.

• HPLC for chromatographic purity against a stated method.
• 1H NMR for the phenyl ring, the 3-methine, and the aminobutanoic chain.
• Mass spectrometry for the free-acid molecular ion consistent with C10H13NO2.
• Chloride content or elemental analysis consistent with the 1:1 hydrochloride.
• Chiral check if the supplier claims the (R) enantiomer.
• Residual solvent if the supplier states it.

Store the COA with the lot number. Do not label the hydrochloride with only the free-acid mass.

Disclaimer

For laboratory research use only. Not for human or veterinary consumption, not for diagnostic or therapeutic use, and not a food, drug, or dietary supplement. Phenibut is not FDA-approved. Health authorities have warned of dependence, withdrawal, and sedation with non-medical use. It is restricted in several countries, including as a scheduled substance in Australia. Legal status varies. Buyers are responsible for confirming legality, import rules, and institutional approval before ordering or handling. Handle with standard laboratory PPE and dispose of waste under local hazardous-chemical rules. No statement on this page is a claim of safety, efficacy, or fitness for any human application.

Frequently asked questions

What is phenibut HCl?
It is the hydrochloride of 4-amino-3-phenylbutanoic acid, a phenyl analogue of GABA. The salt formula is C10H13NO2·HCl, about 215.7 g·mol−1.

Is this the same as the free acid or baclofen?
No. The free acid is CAS 1078-21-3 and weighs 179.22 g·mol−1. Baclofen is the 4-chloro analogue. A milligram of hydrochloride is not a milligram of free acid.

Which CAS number applies?
The free acid is CAS 1078-21-3. The hydrochloride needs the salt identification on the COA. Confirm racemate versus (R) separately from the CAS.

What purity is supplied?
Only the figure on the lot COA. A page-level claim such as ≥98% by HPLC should match the method used for that batch.

How should it be stored?
Sealed, cool, dry, and protected from light. Record the lot number with the COA.

Can it be used in humans?
No. This powder is not sold as a medicine or supplement. Check local law before purchase.

What analytical methods confirm identity?
HPLC purity, NMR for the phenylbutanoic acid, mass spectrometry consistent with C10H13NO2, and a chloride check for the hydrochloride. A chiral assay is needed if the (R) enantiomer is claimed.