Introduction
Metocin 4-HO-MET 21 mg blister is a unit presentation of 4-hydroxy-N-methyl-N-ethyltryptamine, also called metocin or methylcybin. The free base is a 4-hydroxytryptamine with one methyl and one ethyl group on the side-chain nitrogen. It is the 4-hydroxy analogue of MET and the N-ethyl homologue of psilocin (4-HO-DMT). It is also described as a metabolite of 4-acetoxy-MET.
Each blister unit is labeled 21 mg. That number is the declared content of the unit. It is not a recommended amount for any use. The label must state whether 21 mg means free base, fumarate, or another salt, because the same nominal mass is not the same amount of 4-HO-MET.
The blister is a controlled way to present a pre-weighed solid for laboratory identification, content uniformity checks, and reference work. This material is not a medicine, supplement, or diagnostic reagent.
Key features and benefits – Buy Metocin 4-HO-MET 21 mg Blister
- Defined 4-hydroxy scaffold. The 4-hydroxy group distinguishes metocin from MET, and the N-methyl-N-ethyl side chain distinguishes it from psilocin.
- Unit fill. A blister declares 21 mg per unit, which supports content checks without a separate weighing step. Confirm free base versus salt before converting that mass.
- Documented parent identity. Free base CAS 77872-41-4, PubChem CID 21786582, formula C13H18N2O.
- Phenolic marker. The 4-hydroxy group is visible in NMR and UV and separates it from 4-AcO-MET.
- Laboratory-only handling. Intended for controlled chemical and in vitro work, not for formulation or human administration.
Specifications of Buy Metocin 4-HO-MET 21 mg Blister
| Property | Detail |
|---|---|
| Product name | Metocin 4-HO-MET 21 mg blister |
| Chemical name | 3-{2-[Ethyl(methyl)amino]ethyl}-1H-indol-4-ol |
| Synonyms | 4-HO-MET; 4-OH-MET; metocin; methylcybin; 4-hydroxy-N-methyl-N-ethyltryptamine |
| Free-base CAS | 77872-41-4 |
| Free-base identifiers | PubChem CID 21786582; ChemSpider 10513072 |
| Free-base formula | C13H18N2O |
| Free-base molar mass | 218.30 g·mol−1 |
| Labeled content | 21 mg per blister unit |
| Salt form | Must be stated. A 1:1 fumarate is about 334.4 g·mol−1; 21 mg of salt is not 21 mg of free base |
| Appearance | Solid unit in a blister; color depends on form and excipients |
| Purity | As stated on the batch COA (commonly specified ≥98% by HPLC for the active) |
| Solubility | Free base reference data include DMSO and DMF; confirm for the supplied form |
| Storage | Sealed blister, cool, dry, protected from light; 4-hydroxytryptamines oxidize if exposed to air |
| Intended use | Laboratory research only |
Applications in research
Appropriate uses are non-clinical and institutionally approved:
- Analytical reference for HPLC, LC-MS, and NMR identification of 4-HO-MET.
- Content-uniformity checks on a labeled 21 mg unit.
- Forensic differentiation from psilocin, MET, 4-AcO-MET, and 4-HO-MiPT.
- In vitro serotonin-receptor or metabolism assays where the protocol and ethics approval explicitly cover this substance.
- Stability checks of a blistered 4-hydroxytryptamine solid.
Do not describe or imply oral use or any other human route. Do not treat 21 mg as a dose.
Purity and testing
A defensible product claim rests on the batch certificate, not on the blister label alone.
- HPLC for chromatographic purity and for assayed content per unit against the 21 mg label.
- 1H NMR for the 4-hydroxy indole pattern, the N-methyl signal, and the N-ethyl group. An acetyl singlet would indicate 4-AcO-MET rather than 4-HO-MET.
- Mass spectrometry for the free-base molecular ion consistent with C13H18N2O.
- Explicit statement of salt form, and of whether 21 mg is free-base equivalent or salt weight.
- Residual solvent, excipient, and uniformity data if the supplier states them.
Store the COA with the lot number. Do not copy a purity figure from another vendor’s listing.
Disclaimer
For laboratory research use only. Not for human or veterinary consumption, not for diagnostic or therapeutic use, and not a food, drug, or cosmetic. The 21 mg marking is fill weight, not a dosing instruction. 4-HO-MET is a Schedule I controlled substance in Virginia and may be regulated as a controlled substance, analogue, or novel psychoactive substance elsewhere. Buyers are responsible for confirming legality, licensing, import rules, and institutional approval before ordering or handling. Handle with standard laboratory PPE and dispose of waste under local hazardous-chemical rules. No statement on this page is a claim of safety, efficacy, or fitness for any human application.
Frequently asked questions
What is metocin?
Metocin is 4-hydroxy-N-methyl-N-ethyltryptamine (4-HO-MET). It is the 4-hydroxy analogue of MET and a close structural analogue of psilocin.
What does 21 mg on the blister mean?
It is the labeled amount in each unit. It is not a recommended dose. The COA must say whether that 21 mg is free base, fumarate, or another salt.
Is this the same as psilocin or MET?
No. Psilocin is 4-HO-DMT, with two N-methyl groups. MET lacks the 4-hydroxy group. 4-AcO-MET has an acetoxy group at position 4. 4-HO-MET is the free phenol (C13H18N2O, CAS 77872-41-4).
Which CAS number applies?
The free base is CAS 77872-41-4. A salt needs its own identification on the COA.
How should the blister be stored?
Sealed, cool, dry, and protected from light. 4-Hydroxytryptamines can darken or degrade in air. Keep the lot number with the COA.
Can it be used in humans?
No. It is not approved as a medicine and is not sold for consumption. Legal status varies, and it is Schedule I in Virginia. Check local law before purchase.
What analytical methods confirm identity?
HPLC assay against the 21 mg label, NMR for the 4-hydroxy and N-methyl-N-ethyl signals, and mass spectrometry consistent with C13H18N2O. The COA should state salt form so the labeled mass is not read as free-base content.


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