3F-a-PVP Crystal

Introduction

3F-α-PVP crystal is 1-(3-fluorophenyl)-2-(pyrrolidin-1-yl)pentan-1-one. It is a cathinone of the pyrovalerone series. A fluorine sits at the meta position of the phenyl ring, the side chain is a pentanone, and the amine is a pyrrolidine. It is the 3-fluoro analogue of α-PVP. It is not 4F-α-PVP, which has the fluorine at the para position, and it is not α-PVP, which has no fluorine.

It is sold as a forensic reference and is not an approved medicine. The free base weighs 249.33 g·mol−¹. The hydrochloride weighs about 285.8 g·mol−¹, CAS 2748623-76-7. A crystal lot must state which form it is. The alpha carbon is a stereocenter, so racemate versus a named enantiomer should also be stated.

Key features and benefits – Buy 3F-α-PVP Crystal

• Fluorinated pentanone cathinone. The meta-fluoro group is the structural difference from α-PVP and from 4F-α-PVP.
• Documented salt identity. Hydrochloride CAS 2748623-76-7, formula C15H20FNO·HCl, formula weight 285.8.
• Fluorine marker. 19F NMR and the mass defect separate it from α-PVP.
• Weighable solid. Suitable for forensic reference standards when the COA confirms form and fluorine position.
• Laboratory-only handling. Intended for licensed forensic and in vitro work, not for formulation or human administration.

Specifications Of Buy 3F-α-PVP Crystal

Applications in research

Appropriate uses are non-clinical, licensed where required, and institutionally approved:

• Analytical reference for HPLC, LC-MS, and NMR identification of 3F-α-PVP.
• Forensic differentiation from α-PVP, 4F-α-PVP, and 2F-α-PVP.
• Comparison of free-base and hydrochloride crystals.
• In vitro transporter assays where the protocol covers this compound.

Do not describe or imply oral use, insufflation, or any other human route.

Purity and testing

A defensible product claim rests on the batch certificate.

• HPLC for chromatographic purity, with retention that separates the 3-fluoro isomer from the 4-fluoro isomer.
• 1H NMR and 19F NMR for the meta-fluoro aromatic pattern, the pyrrolidine, and the propyl side chain.
• Mass spectrometry for the free-base molecular ion consistent with C15H20FNO. Mass alone does not separate 3F-α-PVP from 4F-α-PVP.
• Explicit statement of free base or hydrochloride.
• Statement of racemate versus enantiomer.
• Residual solvent if the supplier states it.

Store the COA with the lot number. Do not use an α-PVP CAS number for this lot.

Disclaimer

For laboratory research use only. Not for human or veterinary consumption, not for diagnostic or therapeutic use, and not a food, drug, or cosmetic. α-PVP is a Schedule I controlled substance in the United States, and analogue rules may apply to 3F-α-PVP. Other jurisdictions may control it as a cathinone or fluoro-cathinone. Buyers are responsible for confirming legality, licensing, import rules, and institutional approval before ordering or handling. Unauthorized possession can be a criminal offense. Handle with standard laboratory PPE and dispose of waste under local hazardous-chemical rules. No statement on this page is a claim of safety, efficacy, or fitness for any human application.

Frequently asked questions

What is 3F-α-PVP?
It is 1-(3-fluorophenyl)-2-(pyrrolidin-1-yl)pentan-1-one. The free base is C15H20FNO, 249.33 g·mol−¹.

Is the crystal the free base?
Not unless the COA says so. The hydrochloride is CAS 2748623-76-7 and weighs about 285.8 g·mol−¹. Crystal habit does not identify the salt.

Is this the same as α-PVP or 4F-α-PVP?
No. α-PVP has no fluorine. 4F-α-PVP has the fluorine at the para position. 3F-α-PVP is the meta-fluoro pentanone. They share a formula only with other fluoro isomers, not with α-PVP.

Which CAS number applies?
The hydrochloride is CAS 2748623-76-7. Use a free-base number only if the COA assigns it to that form.

What purity is supplied?
Only the figure on the lot COA. A page-level claim such as ≥98% by HPLC should match a method that separates 3-fluoro from 4-fluoro.

How should it be stored?
Sealed, cool, dry, and protected from light and moisture. Record the lot number with the COA.

Can it be used in humans?
No. It is not an approved medicine and is not sold for consumption. Check local law before purchase.

What analytical methods confirm identity?
HPLC with isomer resolution, 1H and 19F NMR for the meta-fluoro pattern, and mass spectrometry consistent with C15H20FNO. Mass alone does not separate it from 4F-α-PVP. The COA should state free base or salt.