Flubromazolam is 8-bromo-6-(2-fluorophenyl)-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine. The content below is written for a research-chemical category page covering flubromazolam materials. It does not include dosing, administration, or human-use claims. Each product requires its own lot-specific COA confirming identity and assay.

Introduction

Flubromazolam is 8-bromo-6-(2-fluorophenyl)-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine. It is a triazolobenzodiazepine related to flubromazepam. A bromine atom sits at the 8-position of the benzodiazepine ring, a fluorine sits at the ortho position of the C6-phenyl ring, and a methyl group sits on the triazole. It is the triazolo analogue of flubromazepam, which lacks the triazole ring.

It is not an approved medicine. The free base is C₁₇H₁₂BrFN₄, 371.21 g·mol⁻¹, CAS 612526-40-6. Products in this category (powder, pellets, or other forms) must state the form on the label and COA. A category name does not confirm the identity of any individual lot.

Key Features & Benefits

• Defined triazolobenzodiazepine. The 8-bromo and 2′-fluoro substitution pattern is the structural marker that distinguishes it from related compounds.
• Documented identity: CAS 612526-40-6, formula C₁₇H₁₂BrFN₄.
• Bromine and fluorine markers. Mass spectra show the bromine isotope pair; ¹⁹F NMR confirms the fluoro pattern.
• Distinct from flubromazepam. That compound lacks the triazole ring (free-base CAS 2647-50-9, C₁₅H₁₀BrFN₂O, 333.16 g·mol⁻¹).
• Suitable for controlled laboratory and forensic analytical work when legally authorized. Not for formulation or human administration.

Specifications Table

Applications in Research

Appropriate uses are non-clinical, institutionally approved, and legally authorized:

• Analytical reference material for HPLC, LC-MS, and NMR identification of flubromazolam against a certified standard.
• Forensic differentiation from flubromazepam and other triazolobenzodiazepines.
• In vitro GABA-A receptor assays where the protocol specifically covers this compound.

Do not describe or imply oral, insufflation, injection, or any other human route of administration. Do not treat any labeled milligram quantity as a dose.

Purity & Testing

A defensible product claim rests on the batch certificate of analysis for the specific form.

• HPLC for chromatographic purity, with retention that separates flubromazolam from flubromazepam.
• ¹H NMR and/or ¹⁹F NMR confirming the 2′-fluoro phenyl pattern and the 8-bromo.
• Mass spectrometry consistent with the free-base molecular ion of C₁₇H₁₂BrFN₄, including the bromine isotope pair.
• Residual solvent and related-substance limits if stated by the supplier.

Store the COA with the lot number. Do not use a flubromazepam CAS number for a flubromazolam lot.

Disclaimer

For laboratory research use only, where legally authorized. Not for human or veterinary consumption, not for diagnostic or therapeutic use, and not a food, drug, or cosmetic. Flubromazolam is a Class C substance in the United Kingdom, Anlage II in Germany, Schedule I in the United States, and Schedule IV in Canada. Flubromazepam is a controlled substance in many jurisdictions, and analogue rules may apply. Unauthorized possession, manufacture, distribution, or importation can be a criminal offense. Buyers are solely responsible for confirming legality, licensing, import rules, and institutional approval before ordering or handling any specific product. Handle under applicable controlled-substance and hazardous-chemical rules and dispose of waste according to local regulations. No statement on this page is a claim of safety, efficacy, or fitness for any human application. The category name does not replace lot-specific identity and purity data on the COA.

Frequently Asked Questions

What is flubromazolam?
It is 8-bromo-6-(2-fluorophenyl)-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine. The free base is C₁₇H₁₂BrFN₄, 371.21 g·mol⁻¹.

Is this the same as flubromazepam?
No. Flubromazepam lacks the triazole ring (CAS 2647-50-9). Flubromazolam has the fused triazole, CAS 612526-40-6. Mass spectra and NMR distinguish them.

Which CAS number applies?
CAS 612526-40-6. Confirm identity and form on the COA.

What purity is supplied?
Only the value stated on the specific lot COA, together with the analytical method. The method should resolve flubromazolam from related compounds.

How should it be stored?
Sealed, cool, dry, and protected from light under the rules that apply. Keep the lot number with the COA.

Can it be used in humans?
No. It is not an approved medicine and is not sold for consumption. In the United Kingdom it is Class C. Check local law before purchase or handling.

What analytical methods confirm identity?
HPLC with related-compound resolution, NMR (including ¹⁹F) for the 2′-fluoro pattern, and mass spectrometry consistent with C₁₇H₁₂BrFN₄ (including the bromine isotope pair). A different substitution pattern means the sample is not flubromazolam.